Summary
Overview
Work History
Education
Skills
Publications
Certification
Courses Taught
Accomplishments
Additional Information
Timeline
Generic

LEEMA GEORGE

Summary

Experienced biotechnology educator with a proven track record of three years in teaching, specializing in molecular biology and genetics. Adept at delivering engaging and informative lessons, fostering a dynamic learning environment. Backed by a year of research experience, I bring practical insights to the classroom, emphasizing the application of biotechnological concepts. Committed to cultivating the next generation of biotechnologists through effective teaching and bridging theory with hands-on research.

Overview

12
12
years of professional experience
1
1
Certification

Work History

Research Associate

Nkure Therapeutics Pvt Ltd
09.2023

Assistant Professor

St. Joseph’s University
08.2021 - 08.2023

Research Scientist

B-Aatral Biosciences Pvt Ltd
01.2021 - 08.2021

Assistant Professor

Jain University
12.2019 - 12.2020

Academic Support Specialist

Biotecnika Info Labs Pvt. Ltd
01.2019 - 05.2019

Research Associate

12.2017 - 12.2018
  • Biotechnology Ignition Grant at VIT, Vellore (Ref No
  • BIRAC/CCAMP0334/BIG-08/16)

Research Associate

School of Bioscience and Technology, VIT
09.2013 - 09.2017

Project Intern

Indian Institute of Science
02.2013 - 04.2013

Guest Lecturer

St. Thomas College
07.2011 - 11.2011

Education

Doctor of Philosophy - Biomedical Science

Vellore Institute of Technology (VIT)
2019

Master of Science - Biomedical Genetics

Vellore Institute of Technology (VIT)
2011

M.Sc. Dissertation -

Bachelor of Science - Botany

Mahatma Gandhi University
2009

Skills

  • Small Laboratory Model Organism Handling: Rodents (Mice , Rat), Drosophila
  • Carrageenan induced paw edema in Rats
  • Cerulein induced acute pancreatitis in Mice model
  • Mammalian Cell Culture:
  • Cell Line Maintenance (RAW 2647macrophage, B16BL6 melanoma cells, A549, HCT-15, MCF-7 cancer cell lines, HEK-293, CHO, Vero, Wharton's jelly-derived mesenchymal stem cells)
  • Primary cell Isolation and Maintenance (Rat bone marrow derived mesenchymal stem cells and, Peripheral Blood Mononuclear Cell (PBMC) Isolation,T cells and NK cells, Mouse peritoneal macrophages, Mouse pancreatic acinar cells,)
  • Cell Viability assay, Cell Proliferation assay
  • Screening of novel anti-cancer and anti-inflammatory compounds
  • Tissue engineering: Experienced in working with collagen scaffolds
  • Molecular Biology: Standard and Real Time PCR (qRT-PCR), ELISA, SDS-PAGE, Western Blotting, Cloning, Transfection (lipofectamine and CaCl2 mediated),Electroporation
  • CRISPR based gene editing
  • Flow Cytometry
  • Microbiology: Experienced in working with Pneumocystis carinii, Screening of anti- virulence compounds
  • Mutagenicity Assays: AMES test, in vitro micronucleus assay, comet assay
  • Cytogenetics Techniques: Karyotyping, G- Banding
  • Analytical Techniques: UV & Fluorescence spectroscopy
  • Microscopy: Fluorescence microscopy
  • Software competency: Graph pad prism, EndNote, Mendeley, Chemdraw, Origin

Publications

  • Leema George, Tamizhselvi Ramasamy, Sirajudeen KNS, Venkatraman Manickam LPS- induced apoptosis is partially mediated by hydrogen sulphide in RAW 264.7 Murine Macrophages. Immunological Investigation 2019 Jan 28:1-15
  • George L, Tamizhselvi. (2018). Protective Effect of Scopoletin Against Cerulein- Induced Acute Pancreatitis and Associated Lung Injury in Mice. Pancreas May/Jun; 47(5):577- 585.
  • Mundekkad Deepa, Leema George, Bhavapriya, Chidambaram Ramalingam (2017). Induction of Apoptosis in HCT-15 and A549 Cell Lines by the Extracts of Excoecaria agallocha L. by the Downregulation of Ornithine Decarboxylase. Brazilian archives of biology and technology (DOI: 10.1590/1678-4324-2017160252)
  • George, L., Ramasamy, T., Manickam, V., Iyer, S. K., & Radhakrishnan, V. (2016). Novel phenanthridine (PHE-4i) derivative inhibits carrageenan-induced rat hind paw oedema through suppression of hydrogen sulfide. Inflammopharmacology 24(4), 173- 180.
  • Hussain, S., Tamizhselvi, R., George, L., & Manickam, V. (2016). Assessment of the role of noni (morinda citrifolia) juice for inducing osteoblast differentiation in isolated rat bone marrow derived mesenchymal stem cells. International journal of stem cells, 9(2), 221.
  • R. Bhavapriya, Leema George, R. Vidya, M. Venkatraman, R. Tamizhselvi and K. I. Sathiyanarayanan. (2015) Antimicrobial assay on synthetic phenanthridine derivatives. Journal of Indian Chemical society 92(6):854-856
  • George, L., Rajendran, B., Manickam, V., Ragothaman, A., Sirajudeen, K., & Tamizhselvi, R. (2014). Psidium guajava leaf extract modulates cytokine expression in lipopolysaccharide-activated primary mouse neutrophils thereby inhibiting NF-κB activity. International Journal of Biological & Pharmaceutical Research. 5(11), 870-875

Certification

Manickam, V., George, L., Tanny, A., Lochana, R., Velusamy, R. K., Kumar, M. M., & Tamizhselvi, R. (2018). Methods and Protocols for In Vitro Animal Nanotoxicity Evaluation: A Detailed Review. Nanotoxicology: Toxicity Evaluation, Risk Assessment and Management, 285.

Courses Taught

  • Immunology: Fundamentals of Immunology, Cells and Organs of The Immune System, Antigens and Antibodies, Innate Immunity and Adaptive Immunity
  • Molecular Biology: DNA Replication, Transcription, Translation, Regulation of Gene Expression
  • Cell Biology: Cell as basic unit of life, Chromosomes and Cell Cycle
  • Developmental Biology : Plant Development and Animal Development
  • Animal Biotechnology: 2D and 3D cell culture



Accomplishments

  • Council of Scientific & Industrial Research, National Eligibility Test (CSIR NET): All India Rank - 31
  • Graduate Aptitude Test in Engineering (GATE) (2013): All India Rank (AIR)-867, Percentile 93
  • TOEFL (2012)-score 95
  • Recognized reviewer of the journal “GENE” (ELSEVIER)

Additional Information

  • University 7th Rank for Bachelor’s Examination VIT Research Award (2016)

Timeline

Research Associate

Nkure Therapeutics Pvt Ltd
09.2023

Assistant Professor

St. Joseph’s University
08.2021 - 08.2023

Research Scientist

B-Aatral Biosciences Pvt Ltd
01.2021 - 08.2021

Assistant Professor

Jain University
12.2019 - 12.2020

Academic Support Specialist

Biotecnika Info Labs Pvt. Ltd
01.2019 - 05.2019

Research Associate

12.2017 - 12.2018

Research Associate

School of Bioscience and Technology, VIT
09.2013 - 09.2017

Project Intern

Indian Institute of Science
02.2013 - 04.2013

Guest Lecturer

St. Thomas College
07.2011 - 11.2011

Doctor of Philosophy - Biomedical Science

Vellore Institute of Technology (VIT)

Master of Science - Biomedical Genetics

Vellore Institute of Technology (VIT)

M.Sc. Dissertation -

Bachelor of Science - Botany

Mahatma Gandhi University
LEEMA GEORGE