P V A Murali Loknath

Qualified B-Tech Professional with experience of +18 years across Pharmaceutical manufacturing, Contract Research and Manufacturing Organization. Currently spearheading as DGM in Process Engineering & Process safety with Laxai Lifesciences Pvt. Limited, Hyderbad location. Expertise in scale-up of API CRAMS and Generic molecules from lab to plant with proven track record of successfully translating laboratory-scale insights into practical and efficient large-scale manufacturing processes. New CDMO APIs technical detailing and to act as single point contact between Customer and Plant. Handled several complex molecules, hazardous reactions and critical & sensitive reactions in commercial scale. Expertise in Process Optimization, Technology transfer & Scale-up of process for API’s, Process safety evaluation, Quality procedures, Health & Safety standards. Process knowledge in identifying the challenges associated to the equipment and troubleshooting the issues for the smooth running of the production campaign. Exoertuze in RC1e studies, DSC studies, Dosing rate calculation for critical additions of reagents based on RC1e study, Mixing study calculations, vent sizing etc., Planning of all products along with new API products without any disturbances/lags and execute plan with 100% equipment utilization. Self-motivated team player with strong communication & presentation skills and proven record of technical accomplishment in challenging roles.

• Providing technical support to the R&D team to develop the robust, scalable and safe process.
• Lab batches monitoring and sharing the experiment details (What-ifs) by considering the scale-up prospective, analyze the outcome of data and provide suggestions.
• Plan pilot experiments with clear objectives, execution preparing pilot study reports.
• Preparing process engineering checklist based on lab experiments for the unit process like reaction and unit operations like filtration, distillation etc.
• Preparing engineering technical package like PFD, P&ID, Equipment suitability, Mass and Material balance sheets, BPR, BCT and Risk assessment documents, and Process engineering calculations.
• Taking lead role in process walkthrough and War room discussion along with CFT teams on BPR, P&ID, Technology packages and Process Safety report to check the fitment of facility and coordinate for completion of pending activities with CFT.
• Leading team of process engineers and guiding them in scale-up of molecules and plant scale executions.
• Providing on-site execution support in batch monitoring and ensuring smooth execution of batches and completion of campaign till delivery.
• Submit the manufacturing updates to the clients and lead the conversation regarding updates, issues and challenges during telecons.
• Taking lead role in completing the investigations of any deviations raised and analyzing the problems, proposing the root cause with experimental evidence and with right CAPA.
• Preparing Campaign reports and Validation reports after completion of batches.
• Preparing RFP with detailed evaluation of the process, check the fitment of manufacturing facilities and submit to Program management / Business Development team within timeline.
• Capacity enhancement and Time cycle reduction proposals.
• Trouble shooting in Production blocks by analyzing and applying technical skills.
• Perform process simulation experiments in Cylindrical vessels.
• Product mapping and capacity calculations for new product enquiries.

• Present CTC: 31.0 Lakhs (Fixed)
• Expected CTC: Negotiable
• Notice Period: 3 months