SACHIN HAMPANNAVAR
Bioprocess Engineer
Summary
Senior Research Associate specializes in establishing project objectives, developing experimental plan and effectively prioritizing tasks to meet time sensitive delivery goals. Serves as point person for executing Discovery, Developmental and Manufacturing research projects and disseminating findings to leadership. Displays strong written and oral communication skills to present complex analyses effectively.
Overview
6
6
years of professional experience
2
2
Certifications
1
1
Language
Work History
Senior Research Associate
Syngene International Limited
Bangalore
10.2021 - Current
- Discovery services Protein engineering and, Expertise with New cell platform EBNA based HEK and CHO cells
- Expertise with stable, transient and viral based transfection methods
- Designed and executed studies to support usability of solutions, analyze data and provide actionable recommendations to project team.
- Achieved project objectives by troubleshooting experiments and testing practical and creative solutions.
- Directed, guided and delegated tasks to teams and developed project schedules, resource requirements and timelines to maintain productivity on goals and objectives.
- Compiled data in reports and other documents using Office 365, distributing to appropriate stakeholders.
- Initiated, planned and executed research projects under supervision of senior scientist.
- Small molecules, large molecules all types of protein were expressed in shake flask and Bioreactors
- Process optimization in Wave bioreactor and Single use bioreactor STR
- Eppendorf and Sartorius based bioreactors
- Process Trouble shooting with protein yield, aggregation, degradation related issues
- Executive Process engineering Virology Department
- Developed data collection strategies and monitored data quality for optimal research results.
- Determined areas of research to increase knowledge in particular field.
Executive
Biological E Limited
Hyderabad
09.2019 - 10.2021
- Familiar with cGMP processes Change control, IQ, OQ, PQ
- Cells handled- Insect, Animal, And Human cell lines (E.g.:SF9, CHO
- HEK, Human fibroblast)
- Worked Hand in hand as a part of MS&T for process Technology transfer
- Introduced new platform for Vaccine production from traditional cell culture method to 3D cell culture
- Cell culture scale up from Roller bottles to cell stacks and to packed bed bioreactor
- Expertise in micro carrier based and suspension cell culture in Bioreactor 5L, 10L, 20L, 50L, 100L, 500L SS and Single use bioreactors
- Preparation of Developmental records, SOP's, BPR's, etc
- Involved in taking preclinical, and clinical batches as per GMP Guidelines
- Had a good exposure with viral cell culture techniques
- Viruses handled:
- Measles, Mumps, Rubella, Hepatitis A, Polio virus, Japanese encephalitis
- Exposure to the outlines of Downstream processes.
- Established clear and competitive goals, growth roadmaps, and strategic business plans.
- Implemented company policies, technical procedures and standards for preserving integrity and security of data, reports, and access.
- Introduced new methods, practices, and systems to reduce turnaround time.
Research Associate
Shilpa Medicare Pvt Ltd, Navya Biological Pvt Ltd
Hubli
06.2017 - 09.2019
- Products handled Blood proteins
- Cell line handled Bacterial- E .coli and Yeast- Pichia pastoris and CHO
- Cells
- Seed inoculum preparation for Bioreactor
- Design and execution of Batch, Fed batch processes and optimization
- Handled scale up experiments in 100L SS production fermenters
- Familiar with PFD and P&ID diagrams modification and analysis
- Sounds good in process trouble shooting and root cause analysis
- Monoclonal antibodies and Fusion proteins early stage process development
- Design and execution of fed batch process for CHO cell derived
- Biosimilars
- Involved in installation and experimentation of process scale up in single use bioreactor.
- Gathered, arranged, and corrected research data to create representative graphs and charts highlighting results for presentations.
- Helped team meet regulatory requirements by coordinating documentation and filings.
- Validated incoming data to check information accuracy and integrity while independently locating and correcting concerns.
- Developed research proposals, identified research objectives and created research plans.
Education
CHEMICALENGINEERING
SDM COLLEGE OFENGINEERING ANDTECHNOLOGY DHARWAD
Dharwad, Karnataka 08.2013 - 03.2017
MBA - Operations Management
University of Petroleum And Energy Studies
Dehradun, Uttrakhand 01.2022 - 01.2024
Skills
Project Management
Quality by Design product development
Bioreactor Scale up
Data Analysis
Experimental design
Technical Writing
Certification
Lean Six Sigma Certified
Timeline
Google certified Project Manager
09-2023
MBA - Operations Management
University of Petroleum And Energy Studies
01.2022 - 01.2024
Senior Research Associate
Syngene International Limited
10.2021 - Current
Executive
Biological E Limited
09.2019 - 10.2021
Lean Six Sigma Certified
06-2019
Research Associate
Shilpa Medicare Pvt Ltd, Navya Biological Pvt Ltd
06.2017 - 09.2019
CHEMICALENGINEERING
SDM COLLEGE OFENGINEERING ANDTECHNOLOGY DHARWAD
08.2013 - 03.2017