Sanjana Shashikanth

Oncology & Precision Medicine Expertise
- I developed and curated high-impact medical and scientific content, including gene–drug–disease interpretations, clinical summaries, and regulatory drug label annotations from the FDA and EMA.
- I also wrote and reviewed evidence-based summaries for NCCN, ASCO, and ESMO guidelines, ensuring accuracy across each release.
- My work included literature reviews for variant interpretations, where I incorporated findings from PubMed, COSMIC, Ensembl, and OncoKB into knowledgebases.

Data, Technology & Compliance
- I collaborated with bioinformatics and software engineering teams to extract insights from NGS data and variant pipelines. This resulted in clinically relevant test case reports and enhancements deployed to production with 100% efficiency and zero failures.
- To maintain regulatory standards, I partnered with software QA and compliance teams, applying SDLC principles to support monthly releases and ensure ISO 13485 compliance.
- I also performed Software Hazard Analyses for IVD devices, helping achieve an 80% reduction in defects in clinical trial datasets.

Leadership & Cross-Functional Collaboration
- I trained junior curators in scientific writing and curation techniques, which raised team effectiveness and documentation standards.
- I translated complex scientific information into client-ready datasets and addressed their requests via JIRA and Zendesk.
Cross-team collaboration was key - I worked closely with colleagues to resolve queries, reduce operational risks, and highlight the role of biocuration for greater transparency.
- As a Scrum lead, I kept stakeholders aligned with sprint updates and metrics, and as a QMS Ambassador, I managed audit-ready documentation that adhered to SDLC principles.

Strategic & Thought Leadership
I- contributed to long-term content strategy by creating standardized documentation templates, defining annotation rules, and establishing quality checkpoints for consistency.
- I also authored a white paper for Velsera, using clinical and competitive data to generate oncology drug discovery insights and propose strategic business improvements.

Clinical Interpretation & Reporting
- I supported clinical interpretation services by analyzing genomic variants and helping generate accurate, actionable clinical reports. My work always aligned with internal guidelines and medical relevance, ensuring clinicians had reliable insights for decision-making.

Clinical Trials Biocuration
- Later, I transitioned into clinical trials biocuration, curating and integrating trial data into internal knowledgebases. This supported precision medicine insights and helped match therapies more effectively to patient profiles.

Process Improvement & Data Quality
- I also implemented process improvements that streamlined data curation workflows and reduced redundancy. Beyond efficiency, I focused on quality, playing a key role in cleaning and validating curated data to strengthen integrity and accuracy.