Venugopal Kamani
Chennai
Summary
I am passionate about analytical science and have an unwavering commitment to quality and innovation. As an aspirant Principal Scientist, I am highly motivated to promoting pharmaceutical research. With over 19 years of experience as an analytical professional, a Ph.D. in Analytical Chemistry, and a wealth of practical knowledge, my goal is to use my expertise in method development, validation, method transfers, Stability studies and compliance to make a significant contribution to innovative initiatives. In order to further refine my skills, maintain the highest standards of scientific investigation, and provide solutions that improve patient safety and health.
Overview
20
20
years of professional experience
Work History
Principle Scientist
Piramal Pharma Limited
Chennai
09.2018 - Current
- Responsible for planning and execution of analytical method developments, Method validations, Method transfers by using Analytical instruments and routine work in AR&D
- Responsible for the review of analytical data, method validation protocols and reports Preparation of request for proposals for new projects and finalize quotations and costing of all analytical projects
- Provided project updates and clarifications in team meetings Attending to Internal phase gate meeting and all customer weekly telecons and sharing of analytical weekly reports
- Prioritize and manage multiple analytical development projects for leading, directing and motivating cross-functional teams to define and achieve the project goals to an agreed time frame, In line with commercial expectations
- Provided feedback on laboratory budget needs and lab associates development need Responsible in qualification and characterization of working / reference standards, data interpretation and Investigation and problem-solving skills Guiding the analytical team for characterization activities and structure elucidation of intermediates, API and impurities using spectroscopic techniques like LCMS, GCMS, IR and NMR
- Ensuring that the projects are delivered as per the quality within the stipulated time frame
- Contribute actively to improve the capabilities within the team and add value to the projects through actively managing resource requirement and providing technical solutions
- Responsible for audit preparations and conducting audits for Internal and external customer
- Maintain the GLP, real time documents, data integrity control measures and safety compliance and ensure that were implemented as per the written SOP’s Implementation of strategic initiations in analytical development lab to improve the efficiency of the process
- Having knowledge on implementation and Procedure of SOPs/Change control /Incidents/Deviations/OOS Ensuring on time testing and releasing of Raw materials, IPC and Intermediates
Research Scientist-II
Neuland laboratories limited
Hyderabad
09.2015 - 08.2018
- Executed HPLC, CHIRAL HPLC UPLC, GC, GCMS, LCMS method developments and validations
- Developed methods using PDA, RID, ELSD, CAD, Mass detectors for API's impurity profiling
- Characterized impurities, standards, and raw materials using spectral techniques
- Prepared characterization reports, certificates of analysis, and method of analysis for various materials
- Supported method development team and provided troubleshooting expertise
- Transferred methods to Quality Control for manufacturing validation
Assistant Manager
Inogent laboratories (GVK Bio company)
Hyderabad
07.2009 - 08.2015
- Hands on experience on development of rugged methods for quantification of low-level impurities and genotoxic impurities by GC, GC-MS, LCMS and HPLC
- Achiral and Chiral HPLC method development, Isolation of degradation impurities from API/CMS compounds, Enantiomers/ Diastereomers /positional isomers etc
- From milligram scale to gram scale by Preparative HPLC and SFC Ensuring the periodic calibration of the instruments present in Analytical Research department
- Prepared the project status presentations and discussions with higher management
Assistant Manager
Sai life sciences
Hyderabad
06.2008 - 05.2009
- Method development and identification of degradation impurities in API compounds, unknown impurities by LCMS and GCMS Developed Methods for API’s by using RID, ELSD, Mass and Impurity profile of low level for API’s for the non UV active & Unionized compounds Periodic calibrations of the instruments in Analytical Research department
Senior Research Associate
GVK BIO
Hyderabad
10.2005 - 05.2008
- Responsible for Analytical Method development for new molecules with short runtime in UPLC, UFLC, RRLC and LCMS for CMS and API molecules with minimum literature available on the structure on the molecule Developed HPLC methods for API’s in PDA &Scaling up for Preparative HPLC purifications Calibration of Instruments and Maintaining Records Implementation GLP in the Lab
Chemist -Quality control
SMS Pharmaceuticals Pvt Ltd
Hyderabad
06.2004 - 06.2005
- Analysis of Raw materials, In-process and finished product analysis by wet chemical Instrumental methods
- Routinely calibrated balances and pH meters Performed tests using Karl Fisher, UV and FTIR
Education
Ph.D. - KL University
01.2023
M.Sc. - Analytical chemistry
01.2005
B.Sc. - Math’s, Physics and Chemistry
01.2002
Skills
- Strategic Planning
- Method Development and transfers
- Method Validations
- Process Improvement/ Innovation
- Troubleshooting and root cause analysis
- Stability studies
- Reference/Working standard qualifications
- Audits and GLP, GMP Compliance
- Customer management
- Report writing and trainings
- Global exposure
- Demonstrative Leadership skills
- Multi-tasking and multidisciplinary skill set
- Data review
- Technical document preparation
- Risk assessments
- Employee Performance Evaluations
Accomplishments
- Rewards & Recognition Award” for the DOW AGRO Projects PREP. purification of 250gm sample for the DOW client at INOGENT (A GVK BIO company)
- Star Performer Award” for the Chiral Prep HPLC purification of 10gm sample for the BI client at GVK-BIO.
- Attended 5 days onsite training on Agilent GCMS at Singapore application Lab
- Attended 3 days onsite training on Waters triple quad & auto purification at Waters Bangalore application Lab.
- Attended 3 days HPLC Method development & validation by Waters University connections.
- One day training on Agilent Ion Trap& Chem Station trouble shooting at Hyderabad.
Personal Information
- Date of Birth: 10/05/1982
- Gender: Male
- Nationality: Indian
- Marital Status: Married
Phone - Cell
0091-8885098878
Patents
Patent No 202241037556: Analysis of Dacomitinib and its related Impurities in bulk and formulations by RPHPC method.
Publications
- Development and validation of a novel stability indicating HPLC method for the separation and determination of darolutamide and its impurities in pharmaceutical formulations, Bulletin of the University of Karaganda – Chemistry, 104(4), 57-68.
- An Innovative Stability Indicating HPLC Method with Impurity Profiling of Niraparib – An Anticancer Drug in Pharmaceutical Formulations, Rasayan Journal of Chemistry, 2022, 15(4): 2976–2983.
- Stability Indicating RP-HPLC Method for the Analysis of Dacomitinib and its Related Impurities in Bulk and Oral Solid Dosage Formulations, Journal of Pharmaceutical Research International, 2021, 33(40B): 187-19.
- Novel Stability indicating High-Performance Liquid Chromatography Method for the Separation and Simultaneous Quantification of Acalabrutinib and Its Impurities in Pharmaceutical Formulation, Analytical Science & Technology, 2023, 36(1): 32-43.
Hobbies and Interests
- Reading books
- Social service
Disclaimer
I hereby declare that the information furnished above is true to the best of my knowledge.
Languages
- English
- Telugu
Timeline
Principle Scientist
Piramal Pharma Limited
09.2018 - Current
Research Scientist-II
Neuland laboratories limited
09.2015 - 08.2018
Assistant Manager
Inogent laboratories (GVK Bio company)
07.2009 - 08.2015
Assistant Manager
Sai life sciences
06.2008 - 05.2009
Senior Research Associate
GVK BIO
10.2005 - 05.2008
Chemist -Quality control
SMS Pharmaceuticals Pvt Ltd
06.2004 - 06.2005